![]() ![]() PROCEDURES Horses were vaccinated against rabies once. The cumulative results from the two challenges shall be evaluated for acceptance as specified in paragraph (b)(3)(v) of this section.OBJECTIVE To investigate the impact of age and inferred prior vaccination history on the persistence of vaccine-induced antibody against rabies in horses.ĪNIMALS 48 horses with an undocumented vaccination history. If one or more of the vaccinates die from rabies, all the remaining vaccinates, regardless of titer, along with the five controls shall be challenged. ![]() All of the challenged vaccinates must remain well for a period of 90 days, and at least 80 percent of the controls must die of rabies for a satisfactory test without further challenge. All SN titers shall be iterated to an endpoint. At least five SN-negative controls of each species shall be challenged at the same time as the vaccinates. ![]() These shall include five vaccinates with the lowest SN titers at the 270th-day bleeding, five vaccinates with the lowest SN titers at the 365th-day bleeding, and all vaccinates with SN titers below 1:10 by the mouse SN test or below 1:16 by the rapid-fluorescent-focus-inhibition test at any bleeding. Vaccinates shall be challenged at 1 year postvaccination. (4) An alternative to challenging all surviving test animals in accordance with paragraph (b)(3)(iv) of this section may be used when the test animals are of species other than carnivores. Contains a highly immunogenic fixed strain of rabies virus that originated from Louis Pasteur’s original 1882 isolate and has been extensively tested for freedom from contaminating agents. DEFENSOR vaccines contain inactivated rabies virus from an established cell line. NOTE: Previously vaccinated patients include those who received a complete vaccination series (pre- or postexposure prophylaxis) with a cell-culture vaccine or who previously had a documented adequate rabies virus-neutralizing antibody titer after vaccination with other types of vaccines. For postexposure vaccination of previously vaccinated persons. Vaccines are one of the greatest public health advancements of all time, resulting in the control, elimination, or near-elimination of numerous infectious diseases that were once pervasive and often fatal. IMRAB, world leader in rabies prevention1 IMRAB offers many unique advantages to veterinarians - and the animals in their care: IMRAB 3 is indicated for use in six species (dogs, cats, ferrets, horses, cattle, and sheep), so clinics only need to stock a single rabies vaccine Three-year duration of immunity in dogs, cats, and sheep2 One-year duration of immunity in horses. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |